Understanding how the estrogen receptor impacts breast cancer

Hello! My name is Bart Kolendowski and I’m a PhD candidate in the Department of Biochemistry at Western University. I work in Dr. Joe Torchia’s lab located at London Regional Cancer Program.
Bart KolendowskiDuring my tenure as a Pamela Greenaway-Kohlmeier Translational Breast Cancer Research Unit (TBCRU) scholarship recipient, I have focused my research on understanding how the estrogen receptor, a common target during breast cancer therapy, impacts breast cancer. By developing our understanding of how the estrogen receptor functions, we not only learn about how certain breast cancer therapies work but also why they may fail. With the support of TBCRU funding I have been able to advance our understanding of estrogen-mediated gene-expression, identifying previously unknown mechanisms that drive breast cancer development.

This work has been well received and has given me the opportunity to present my findings at prestigious conferences, including the Canadian Institutes of Health Research National Student Research Competition held at the University of Winnipeg. I was also selected for an oral presentation at the international Keystone Symposia on Nuclear Receptors held in Snowbird, Utah. I am excited as my research is currently being compiled into a manuscript for submission to an academic journal to be shared with a broader audience.

In addition to helping advance my research, the TBCRU scholarship has promoted researchers’ engagement with the community through events like the Breast Cancer Society of Canada’s Mother’s Day Walk. These events allow researchers to meet and hear the stories of survivors and their families while also giving us an opportunity to share our work with them, successfully bridging the world of research with the people it impacts.

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